dGEMRIC (delayed Gadolinium Enhanced Magnetic Resonance Image of Cartilage) is a well-established technique for cartilage quality assessment in osteoarthritis at clinical field strengths. The method is robust, but requires injection of contrast agent and a cumbersome examination procedure.

Three-dimensional T1 quantification techniques for assessment of cartilage quality using dGEMRIC(Carl Siverssons doktorsavhandling)

Y1 - 2015 dGEMRIC (delayed Gadolinium Enhanced Magnetic Resonance Image of Cartilage) is a well-established technique for cartilage quality assessment in osteoarthritis at clinical field strengths. The method is robust, but requires injection of contrast agent and a cumbersome examination procedure. According to the decrease of glycosaminoglycans in cartilage degeneration, more Gd-DTPA2 penetrates into the cartilage, which will cause a reduction of T1 relaxation time that can be measured in milliseconds - "Current knowledge and importance of dGEMRIC techniques in diagnosis of hip joint diseases" (dGEMRIC) has been shown to be a clinically useful tool for assessing the glycosaminoglycan (GAG) content in cartilage (1–4). Proteoglycans (PGs) are major contrib-utors to the compressive stiffness of cartilage, and are lost in the early stages of osteoarthritis (5).

Dgemric technique

dGEMRIC requires intravenous injection of gadolinium contrast, however, which adds time, expense, and 2013-07-01 2012-10-01 2013-12-20 Purpose: To determine the feasibility of using a high resolution isotropic three-dimensional (3D) fast T1 mapping sequence for delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) to assess osteoarthritis in the hip. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) is sensitive to the glycosaminoglycan content in cartilage that is lost early in the development of osteoarthritis (OA). Hence, the dGEMRIC technique holds promise for the development of … 2018-05-16 The delayed Gadolinium Enhanced Magnetic Resonance Imaging of Cartilage (dGEMRIC) technique is a well- established method for early assessment of cartilage quality in osteoarthritis. Using this technique, the distribution of Gd-(DTPA)2−contrast agent in cartilage after intravenous injection is assessed with quantitative T1 To determine whether either of two magnetic resonance imaging approaches - delayed gadolinium enhanced magnetic resonance imaging of cartilage (dGEMRIC), or T2 mapping - can detect short-term changes in knee hyaline cartilage among individuals taking a formulation of collagen hydrolysate. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a new technique to study cartilage glycosaminoglycan (GAG) content.

found a mean T1 RT of 427 ± 159 ms and a mean T1 RC of 636 ± 189 ms.

MRI of Cartilage (dGEMRIC) technique. [2, 3] into our routine clinical imaging protocol. We have previously shown that. dGEMRIC technique for the hip corre-.

Bostelmann R(1), Bostelmann T(2), Nasaca A(2), Steiger HJ(2), Zaucke F(3), Schleich C(4). 2015-04-26 · Hence, the dGEMRIC technique holds promise for the development of new diagnostic and therapeutic procedures.

Herein, we describe the dGEMRIC technique using a new positively charged contrast agent (i.e. dGEMRIC+). Specifically, we report: the synthesis and

as a method Although some techniques such as delayed gadolinium-enhanced MRI of cartilage (dGEMRIC). [19] require the administration of a contrast agent, others such. Jan 20, 2021 Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is the gold-standard technique for compositional cartilage imaging that allows the Summary. Objective: Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) reflects cartilage In the dGEMRIC technique, the negatively charged con-. Jun 29, 2011 Therefore, the dGEMRIC technique has a potential to detect early cartilage damage that is obviously critical for decision-making regarding time Delayed gadolinium-enhanced magnetic resonance imaging of cartilage ( dGEMRIC) is sensitive to the glycosaminoglycan content in cartilage that is lost early in What Is the Correlation Among dGEMRIC, T1p, and T2* Quantitative MRI Cartilage Mapping Techniques in Developmental Hip Dysplasia? Melkus, Gerd PhD Herein, we describe the dGEMRIC technique using a new positively charged contrast agent (i.e. dGEMRIC+).

(dGEMRIC) is a non-invasive imaging method that measures a surrogate for glycosaminoglycan (GAG) concentration in articular cartilage [1]. GAG is a macromolecule whose con- (dGEMRIC) has been shown to be a clinically useful tool for assessing the glycosaminoglycan (GAG) content in cartilage (1–4).
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Hence, the dGEMRIC technique holds promise for the development of … Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) was first described in 1996 as a nondestructive technique for quantitative measurements of glycosaminoglycan (GAG) concentration in articular cartilage samples [].Its translation to clinical platforms as a means of interrogating the molecular aspects of cartilage was demonstrated in 1997 with illustrative examples of apparent … 2012-10-01 (dGEMRIC) is a non-invasive imaging method that measures a surrogate for glycosaminoglycan (GAG) concentration in articular cartilage [1]. GAG is a macromolecule whose con- Background: Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a validated technique for evaluating cartilage health in developmental dysplasia of the hip (DDH), which can be a helpful prognosticator for the response to surgical treatments. dGEMRIC requires intravenous injection of gadolinium contrast, however, which adds time, expense, and 2013-07-01 2013-12-20 Purpose: To determine the feasibility of using a high resolution isotropic three-dimensional (3D) fast T1 mapping sequence for delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) to assess osteoarthritis in the hip.

dGEMRIC+). Specifically, we report: the synthesis and Methods: dGEMRIC, T2 and native T1 relaxation times of healthy mature human, juvenile porcine technique for reliable assessment of the cartilage PG con-.
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trastförstärkt MR (dGEMRIC), där man försöker *Compared to existing techniques for single tunnel ACL reconstruction. operative technique and preliminary.

/ Tiderius, Carl Johan. Medicinsk Informationsteknik, Malmö, 2004. 120 p.

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Found 5 swedish dissertations containing the words delayed gadolinium-enhanced MRI of cartilage dGEMRIC. 1. Three-dimensional T1 quantification techniques

Specifically, we report: the synthesis and Methods: dGEMRIC, T2 and native T1 relaxation times of healthy mature human, juvenile porcine technique for reliable assessment of the cartilage PG con-. Nov 10, 2016 Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) allows an dGEMRIC provides a non-invasive method of assessing these effects. Methods.